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Serge Renaud,
Dominique Lanzmann-Petithory,
Emile Roux Hospital,
Public assistance of
Paris Hospitals France
René GUEGUEN
and Pascale CONARD
Center of Preventive Medicine,
Nancy, France |
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Wine
and risk factors related to
all-cause mortality
Risk factors such as serum cholesterol and smoking have
been associated not only with
cardiovascular but also with mortality from all causes.
Since in France the risk factors seem to be as high
as in other countries such as USA and Great Britain
(14), we have evaluated, in the Nancy cohort, the effect
that wine drinking would have on the risk of death.
As shown in Figure 3, serum cholesterol in Eastern
France does not appear to be associated with an increased
risk of death from all-causes. Nevertheless, it is interesting
to note that independent of the serum cholesterol level,
the deaths from all-causes in wine drinkers is 22 to
32% lower than in non-drinkers or the other drinkers.
Figure 4 shows the effects of alcoholic beverages on
the risk of mortality from all causes in relation to
smoking. Contrarily to what happens with cholesterol,
in our cohort, smoking not only increases the risk of
cardiovascular diseases but also increases the risk
of death from all-causes by 4-fold in heavy smokers.
The other drinkers present a similar risk than the non-drinkers
while the wine drinkers present a lower risk of 18 to
29 %. |
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Figure 2. Death by cancer in wine drinkers of the Nancy
cohort.
Relative risk of death in relation to the intake of
wine compared to abstainers, adjusted as in Figure 1.
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Figure 3. Death from all-causes
in relation to serum cholesterol in the Nancy cohort.
Relative risk of death in relation to the intake of
wine or of other alcohol beverages compared to abstainers,
adjusted for age, smoking, education, physical activity,
blood pressure and BMI. |
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Figure 4. Death from all-causes
in relation to smoking in the Nancy cohort.
Relative risk of death in relation to the intake of
wine or of other alcohol beverages compared to abstainers,
adjusted for age, cholesterol, education, physical activity,
blood pressure and BMI. |
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Guide des vins "Vins et Santé"