Conclusion
A high number of prospective studies have observed that
a moderate intake of alcoholic beverages may protect
from cardiovascular diseases, morbidity and mortality.
Recent studies on all-cause mortality suggest that only
wine at very moderate intake, may be beneficial, through
its
effects on cancer and other causes (15, 16).
Even risk factors such as serum cholesterol and smoking
do not seem to impede the protective effect of moderate
wine drinking on all-cause mortality.
Therefore, the protective effect of wine drinking on
the effects of certain risk factors seems to be the
direct explanation of the French Paradox, a low mortality
rate despite a level of risk factors similar to that
of countries such as USA and Great Britain. |
|
Références
1. RIMM EB, GIOVANNUCCI EL, WILLETT WC, COLDITZ GA,
ASCHERIO A, ROSNER B, STAMPFER MJ.(1991) Prospective
study of alcohol consumption and risk of coronary
disease in men. Lancet 338:464-468
2. KAGAN A, YANO K, RHOADS GG, McGEE DL (1981) Alcohol
and cardiovascular disease: the Hawaiian experience.
Circulation 64: III 27-31
3. SHAPER AG, WANNAMETHEE G, WALKER M (1994) Alcohol
and coronary heart disease: a perspective from the
British Regional Heart Study. Int
J Epidemiol 23:482-494
4. LEINO EV, ROMELSJO A, SHOEMAKER C, AGER CR, ALLEBECK
P, FERRER HP, FILLMORE KM, GOLDING JM, GRAVES KL,
KNIEP S. (1998) Alcohol consumption and mortality.
II. Studies of male populations. Addiction 93:205-218
5. DOLL R, PETO R, HALL E, WHEATLEY K, GRAY R (1994)
Mortality in relation to consumption of alcohol: 13
years’ observations on male British doctors.
BMJ 309:911-918
6. CAMARGO CA JR, HENNEKENS CH, GAZIANO JM, GLYNN
RJ, MANSON JE, STAMPFER MJ (1997) Prospective study
of moderate alcohol consumption and mortality in US
male physicians. Arch Intern Med 157:79-85
7. THUN MJ, PETO R, LÓPEZ AD, MONACO JH, HENLEY
SJ, HEATH CW JR, DOLL R. (1997) Alcohol consumption
and mortality among middleaged and elderly U.S. adults.
N Engl J Med 337:1705-1714
8. GRØNBÆK M, DEIS A, SØRENSEN
TI, BECKER U, SCHNOHR P, JENSEN G (1995) Mortality
associated with moderate intakes of wine, beer, or
spirits. BMJ
310:1165-1169
9. RENAUD SC, GUEGUEN R, SCHENKER J, d’HOUTAUD
A (1998) Alcohol and mortality in middle-aged men
from eastern France. Epidemiology 9: 184-188
10. RENAUD SC, GUEGUEN R, SIEST G, SALAMON R (1999)
Wine, beer, and mortality in middle-aged men from
eastern France. Arch Intern Med 159:1865-1870
11. GRØNBÆK M, BECKER U, JOHANSEN D,
GOTTSCHAU A, SCHNOHR P, HEIN HO, JENSEN G, SØRENSEN
TI. (2000) Type of alcohol consumed and mortality
from all causes, coronary heart disease, and cancer.
Ann Intern Med 133:411-419
12. GRØNBÆK M, BECKER U, JOHANSEN D,
TONNESEN H, JENSEN G, SØRENSEN TI (1998) Population
based cohort study of the association between alcohol
intake and cancer of the upper digestive tract. BMJ
317:844-847
13. JANG M, CAI L, UDEANI GO, SLOWING KV, THOMAS CF,
BEECHER CW, FONG HH, FARNSWORTH NR, KINGHORN AD, MEHTA
RG, MOON RC, PEZZUTO JM. (1997) Cancer chemopreventive
activity of resveratrol, a natural
product derived from grapes. Science 275:218-220
14. KUULASMAA K, TUNSTALL-PEDOE H, DOBSON A, FORTMANN
S, SANS S, TOLONEN H, EVANS A, FERRARIO M, TUOMILEHTO
J. (2000) Estimation of contribution of changes in
classic risk factors to trends in coronary-event rates
across the WHO MONICA Project populations. Lancet
355:675-687
15. GRØNBÆK M, JENSEN MK, JOHANSEN D,
SØRENSEN TIA, BECKER U (2004) Intake of Beer,
Wine and Spirits and Risk of Heavy Drinking and Alcoholic
Cirrhosis. Biol Res 37: 195-200
16. LETENNEUR L (2004) Risk of Dementia and Alcohol
and Wine Consumption: a Review of Recent Results.
Biol Res 37: 189-193 |
Guide des vins "Vins et Santé"